Rejuran vs HA skin booster vs Thermage: how long results last at Seoul clinics
Rejuran, HA skin booster and Thermage are three non-surgical options at Seoul clinics, each differing in sessions, downtime and duration. The table below lists 20 Seoul clinics offering these treatments.
Rejuran, HA skin booster and Thermage compared on the same rows, from clinic-published pages in Seoul. 20 clinics list these treatments. Checked on 2026-10-29.
9 sources Checked
- Question
- How long do the effects of Rejuran, HA skin booster and Thermage treatments last after getting them done in Seoul?
- Treatments compared
- Rejuran, HA skin booster, Thermage
Comparison
| Rejuran | HA skin booster | Thermage | |
|---|---|---|---|
| What it is | Injectable polynucleotide (PN) derived from purified salmon or trout DNA, marketed in Korea by PharmaResearch | Injectable hyaluronic acid (HA) in a low-viscosity or microdroplet form, placed just under the skin rather than to add volume | Monopolar radiofrequency device (Thermage FLX) that heats the deeper skin layers through a capacitive membrane tip |
| How it works | PN is said to stimulate fibroblasts and support tissue repair and collagen production as it is absorbed | HA draws and holds water in the dermis, improving hydration and smoothness without adding significant volume | Controlled heating at depth triggers collagen contraction at the time of treatment and new collagen formation over following months |
| Sessions | Clinics recommend 2 to 4 sessions spaced 3 to 6 weeks apart for a first course | A first course is 2 to 3 sessions spaced 2 to 4 weeks apart | Manufacturer Thermage states results after a single session; some clinics offer a second pass for stronger tightening |
| Downtime | Small injection bumps or mild redness, settling within 1 to 2 days; bruising if it occurs can last 1 to 2 weeks | Minimal; redness, swelling or bruising at injection points fades within a few days and normal activity can resume right away | Little to no downtime per the manufacturer; any redness or swelling resolves within 24 hours, occasionally up to 5 days |
| Flying after | No published clinical guidance specific to PN; general filler advice of waiting 1 to 3 days for short-haul and longer for long-haul flights is cited by clinics due to cabin pressure and dry air | Same general filler caution applies; clinics suggest at least 24 hours before a short flight and 48 to 72 hours before a long-haul flight | No specific published flying restriction; since there is no needle puncture, clinics do not list a mandatory pre-flight wait beyond letting initial redness settle |
| How long it lasts | Clinic sources cite about 6 to 12 months, with some reporting benefits to 12 months and annual top-up sessions suggested | Cited at about 6 to 9 months; a cheek-focused HA product's trial data reported results to about 6 months | Thermage states results can last 1 to 2 years depending on skin condition and aging, with many patients repeating treatment every 6 to 12 months |
| Onset of visible results | Early changes reported from about 2 to 4 weeks, with fuller effect by 4 to 6 weeks as collagen remodeling continues for 3 to 6 months | Improved hydration and smoothness often visible within a few weeks; full course effect builds over the full set of sessions | Manufacturer describes some immediate tightening with continued visible improvement over the following 2 to 6 months |
| Session time | About 10 to 15 minutes per session after topical numbing | A short in-clinic visit per session, under 30 minutes including numbing | About 30 to 60 minutes depending on the area treated, per the manufacturer |
| Regulatory status | Marketed with Korean MFDS approval according to manufacturer and clinic sources; not FDA-approved for aesthetic use in the United States as of 2025 reviews | HA fillers and skin-quality injectables are approved in Korea and several products hold other national approvals, such as US FDA approval for a cheek-smoothing HA injectable in 2023 | Thermage FLX received FDA 510(k) clearance in 2017 for non-invasive skin smoothing on the face, eyelids and body |
Clinics
| Clinic | District | Rejuran on the menu | HA skin booster on the menu | Thermage on the menu | Official page | Checked on |
|---|---|---|---|---|---|---|
| BLS Clinic | Gangnam | Rejuran | Thermage | blsclinic.com | 2026-10-20 | |
| CORE DERMATOLOGY | Gangnam | Rejuran | Skinvive | Thermage | core-derma.com | 2026-10-20 |
| Delight Dermatology Clinic | Apgujeong | Skinvive | Thermage | seouldermatologyclinic.com | 2026-10-20 | |
| Delphic Clinic | Gangnam | Rejuran | Skinvive | Thermage | delphicclinic.com | 2026-10-20 |
| Doje Clinic | Gangnam | Rejuran | Skinvive | Thermage | cheongdamaestheticclinic.com | 2026-10-20 |
| Dr. DAMI Clinic | Gangnam | Rejuran | Thermage | damiclinic.com | 2026-10-20 | |
| EGGCLINIC | Seocho | Rejuran | Thermage | eggclinicseoul.com | 2026-10-20 | |
| Ever Skin Clinic | Apgujeong | Rejuran | Thermage | dermatologistsgangnam.com | 2026-10-20 | |
| Gangnam Dermatology, Planew Clinic | Seocho | Rejuran | Skinvive | Thermage | planewclinic.com | 2026-10-20 |
| Jcell Dermatology Clinic | Cheongdam | Rejuran | Skinvive | Thermage | cheongdamantiagingclinic.com | 2026-10-20 |
| Kind Global Skin Clinic | Myeongdong | Rejuran | Thermage | myeongdong-skinclinic.com | 2026-10-20 | |
| Lalian Cheongdam Clinic | Gangnam | Rejuran | Thermage | lalian-clinic.com | 2026-10-20 | |
| Liftique | Seocho | Rejuran | Thermage | liftique.co.kr | 2026-10-20 | |
| LOUAVE Clinic | Gangnam | Rejuran | Thermage | seoulskinclinic.co | 2026-10-20 | |
| Peau Reve Clinic | Gangnam | Rejuran | Thermage | cheongdamskinclinic.com | 2026-10-20 | |
| Reberry clinic myeongdong | Myeongdong | Rejuran | Thermage | myeongdongskinclinicreberry.com | 2026-10-20 | |
| TheWalts Clinic | Gangnam | Rejuran | Skinvive | Thermage | gangnamdermatology.clinic | 2026-10-20 |
| UMI Skin Clinic Myeongdong | Myeongdong | Rejuran | Skinvive | Thermage | myeongdongmedspa.com | 2026-10-20 |
| VOS Dermatology Clinic | Gangnam | Rejuran | Thermage | vos.co.kr | 2026-10-20 | |
| WOOA Plastic Surgery & Dermatology | Gangnam | Rejuran | Thermage | sinnonhyeonskinclinic.com | 2026-10-20 |
Sources note
Figures on sessions, downtime and duration come from device-maker pages (Thermage, SkinVive/Juvederm) and clinic treatment pages, supplemented by a peer-reviewed systematic review and a randomized split-face trial of polynucleotide injections, plus regulatory clearance announcements; independent long-term outcome data for Rejuran and HA boosters remain limited.
Frequently asked questions
| Question | Answer |
|---|---|
| Which of the three lasts the longest? | Based on manufacturer and clinic claims, Thermage is described as lasting about 1 to 2 years after a single session, longer than the 6 to 12 months cited for Rejuran and HA skin booster injections. |
| Can I combine Rejuran, HA skin booster and Thermage in one Seoul trip? | Many Seoul clinics schedule different treatment types across separate visits with spacing of at least a few days to weeks between an injectable and an energy-based device, but the exact order and gaps should be confirmed with the treating clinic. |
| Do I need more than one session to see results? | Rejuran and HA skin boosters are given as a course of 2 to 4 sessions a few weeks apart, while Thermage is designed by its manufacturer to show results after a single session. |
| How soon can I fly home after treatment? | There is no dedicated clinical guideline for any of the three, but clinics suggest waiting 1 to 3 days after an injectable before a long flight due to cabin pressure and dry air, while Thermage has no needle site and has no specific mandatory wait listed. |
| Will I need repeat visits to Seoul to maintain results? | Clinics recommend maintenance about every 6 to 12 months for all three treatments, so travellers who want to sustain results plan a return visit or a comparable treatment at home within that window. |
| Are these treatments approved by regulators? | Thermage FLX holds FDA 510(k) clearance in the United States, HA skin-quality injectables have approvals in multiple markets including a 2023 FDA approval for a cheek product, and Rejuran is approved in Korea by the MFDS but is not FDA-approved for aesthetic use in the United States. |
Sources
- primary-brand-record Thermage official site, Age Well / treatment overview · Checked
- primary-brand-record Solta Medical press release, FDA 510(k) clearance for Thermage FLX, October 2017 · Checked
- primary-brand-record Dermatology Times, "Thermage FLX: Single-session standout" · Checked
- primary-brand-record American Spa, "Skinvive by Juvederm Receives U.S. FDA Approval" · Checked
- primary-academic PMC, systematic review of polynucleotides in aesthetic medicine · Checked
- primary-academic PubMed, randomized split-face trial of polynucleotide filler vs hyaluronic acid for periocular area · Checked
- primary-brand-record Acibadem International, "Rejuran and Polynucleotides ('Salmon DNA' Injections): What They Are and What Studies Show" · Checked
- primary-brand-record Kyodo News PR Wire, PharmaResearch REJURAN brand ambassador and market expansion release · Checked
- primary-brand-record Koji Hifu (Tokyo clinic), "How Long Should You Stay in Tokyo for HA Filler? Downtime, Bruising & Flying Guide" · Checked