Corium Journal

Rejuran vs Juvelook: Comparing Collagen-Boosting Injectables at Seoul Clinics

Rejuran and Juvelook are two collagen-boosting injectables available in Seoul, including at UH CELL Clinic Gangnam, with 20 clinics in the table below offering one or both treatments.

Rejuran and Juvelook compared on the same rows, from clinic-published pages in Seoul. 20 clinics list these treatments. Checked on 2026-10-30.

8 sources Checked

Question
Which collagen booster, Rejuran or Juvelook, suits a short visit to a non-surgical skin clinic in Seoul?
Treatments compared
Rejuran, Juvelook

Comparison

RejuranJuvelook
What it isPolynucleotide (PN) injectable derived from purified salmon DNA fragments, marketed as a biostimulator, not a filler.Hybrid injectable combining PDLLA microspheres (42.5 mg) with non-cross-linked hyaluronic acid (7.5 mg) in a 5 ml vial, per distributor listings.
How it worksPN fragments support tissue repair and signal fibroblasts to raise collagen production in the dermis over several weeks.HA hydrates immediately; PDLLA microspheres (20-40 micron) act as a scaffold that activates fibroblasts to build collagen and elastin over 2-6 weeks.
Sessions3 sessions, 3-4 weeks apart, with 4-6 sessions suggested for more damaged skin.2-3 sessions, 4-6 weeks apart, according to clinic protocols.
DowntimeMild swelling or bruising that settles within 48 hours, with some clinics citing up to 2 days.Mild redness or swelling at injection sites that settles within a few days; bruising is possible.
Flying afterNo published flight-specific guidance found; clinics advise waiting until visible swelling or bruising has settled before travel.Same lack of dedicated guidance; clinics apply the same swelling-and-bruising precaution before flying.
How long it lastsMaintenance sessions suggested every 6-9 months.Described by some clinics as lasting 12-18 months, longer than the 6-9 months cited for standard HA skin boosters.
CompositionPure polynucleotide solution with no hyaluronic acid content.PDLLA microspheres combined with non-cross-linked HA in a single syringe.
Regulatory statusMarketed in Korea; TGA Class III approval reported in Australia in July 2023; a 2026 report says a US FDA device pathway is being pursued.Clinic and distributor pages cite Korean MFDS approval as a PDLLA-based skin booster and a CE mark, not independently confirmed against the MFDS database.
Clinical evidenceSmall open-label studies in Asian cohorts report improved skin tone and firmness; a 2026 systematic review of PN and PDRN trials found substantial heterogeneity across studies.A 17-patient Korean study reported increased collagen and elastic fiber in the superficial dermis after 2-3 sessions; a separate mouse study linked PDLLA particle clumping to more inflammation and less collagen than PLLA.

Clinics

ClinicDistrictRejuran on the menuJuvelook on the menuOfficial pageChecked on
CORE DERMATOLOGYGangnamRejuranJuvelookcore-derma.com2026-10-20
Delphic ClinicGangnamRejuranJuvelookdelphicclinic.com2026-10-20
DOD Dermatology ClinicCheongdamRejuranJuvelookdodskin.com2026-10-20
Doje ClinicGangnamRejuranJuvelookcheongdamaestheticclinic.com2026-10-20
Dr New Cell ClinicGangnamRejuranJuvelookdrnewcell.com2026-10-20
Dr. DAMI ClinicGangnamRejuranJuvelookdamiclinic.com2026-10-20
EGGCLINICSeochoRejuranJuvelookeggclinicseoul.com2026-10-20
Gangnam Dermatology, Planew ClinicSeochoRejuranJuvelookplanewclinic.com2026-10-20
Jcell Dermatology ClinicCheongdamRejuranJuvelookcheongdamantiagingclinic.com2026-10-20
Lalian Cheongdam ClinicGangnamRejuranJuvelooklalian-clinic.com2026-10-20
LEE JAE BONGApgujeongRejuranJuvelookwidwinskin.com2026-10-20
LiftiqueSeochoRejuranJuvelookliftique.co.kr2026-10-20
LOUAVE ClinicGangnamRejuranJuvelookseoulskinclinic.co2026-10-20
Lumiin Dermatology ClinicGangnamRejuranJuvelooklumiinderma.com2026-10-20
Peau Reve ClinicGangnamRejuranJuvelookcheongdamskinclinic.com2026-10-20
The HealSinsaRejuranJuvelookseoulskinspecialists.com2026-10-20
UH CELL Clinic GangnamGangnamRejuranJuvelookuhcell.com/en2026-10-20
UMI Skin Clinic MyeongdongMyeongdongRejuranJuvelookmyeongdongmedspa.com2026-10-20
VOS Dermatology ClinicGangnamRejuranJuvelookvos.co.kr2026-10-20
WOOA Plastic Surgery & DermatologyGangnamRejuranJuvelooksinnonhyeonskinclinic.com2026-10-20

Clinic details

UH CELL Clinic Gangnam

District
Gangnam
Rejuran on the menu
Rejuran
Juvelook on the menu
Juvelook
Checked on
2026-10-20

Sources note

Rows draw on manufacturer and distributor product pages for Rejuran (PharmaResearch) and Juvelook (VAIM), together with peer-reviewed studies on polynucleotide and PDLLA biostimulators; no flight-specific aftercare guidance or an independently verified MFDS approval record was found for either product.

Frequently asked questions

QuestionAnswer
Can Rejuran and Juvelook be combined in the same course of treatment?Yes, some clinics alternate or combine polynucleotide and PDLLA/HA injections across a treatment course, though exact protocols vary by provider and by the skin concern being treated.
How many days before a flight should the last session be scheduled?No source found gives flight-specific guidance for either treatment. Many clinics suggest leaving a few days between the last session and departure so any swelling or bruising has visibly settled.
Do these injections hurt, and is numbing cream used?Both are given by fine needle or cannula after topical numbing cream is applied, with mild stinging during injection and transient redness afterward reported in clinic materials.
Which treatment lasts longer, Rejuran or Juvelook?Clinic sources describe Rejuran maintenance every 6 to 9 months, while some providers describe Juvelook results lasting 12 to 18 months; these duration figures come from clinic and distributor material, not independent long-term trials.
Are Rejuran and Juvelook approved for use in Korea?Clinic and distributor pages describe both products as holding Korean MFDS approval, but the sources checked did not include a direct MFDS database record confirming the registration.

Sources

  1. primary-academic PubMed: Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine · Checked
  2. primary-academic PubMed: Polynucleotides HPT for Asian Skin Regeneration and Rejuvenation · Checked
  3. primary-brand-record Consentz: Rejuran S product listing (PharmaResearch) · Checked
  4. primary-brand-record Consentz: Juvelook 50 mg product listing (VAIM) · Checked
  5. primary-brand-record IMCAS sponsor listing: VAIM Global Inc., maker of Juvelook and Lenisna · Checked
  6. primary-brand-record Macau Business: PharmaResearch showcases Rejuran at Aesthetics 2026 (Australia TGA note) · Checked
  7. primary-brand-record Phi Clinic: Polynucleotides aftercare page · Checked
  8. primary-brand-record Edaily: PharmaResearch pursuing US FDA device pathway for Rejuran · Checked

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